Author Topic: TREHALOSE - Educational Paper by JC Spencer  (Read 4910 times)

kendersa

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TREHALOSE - Educational Paper by JC Spencer
« Reply #3 on: March 26, 2008, 11:52:24 AM »
martyk its so nice to meet you!

Hearing your story and the great results you are getting at being able to control tremors with Trehalose brings me so much joy! My family has been using it for the past month and a half and has been getting great results as well (completely controlling calf tremors.)  I am hoping that in more time we will be seeing even greater results.  Have you been able to see a consistent change for the better as the months go by with your daughter?  I am constantly searching for promising results to be able to tell my brother who currently has been showing signs of HD for the past 3 years.  Sometimes the HD gets the better of him and he doesn't think Trehalose is worth it and thinks he should stop taking it.  But I am always trying to show him how positive it has been so far for him and I would love to be able to tell him that with each month it has been getting better for your daughter as well.
« Last Edit: May 05, 2008, 03:36:14 PM by JC Spencer »

martyk

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TREHALOSE - Educational Paper by JC Spencer
« Reply #2 on: March 01, 2008, 11:51:41 AM »
I am delighted to see this forum happening. I have years of experience with Huntington Disease in my family.
Presently my daughter is getting very good results, with control of her first appearing tremmors. She has been using the Trehalose as a sweetener for  her drinks for about 6 months now and will continue to use it for her life.

What  I see in her, gives me great hope, that she will postpone her expected full onset of Huntinton Disease for a long time, and I pray, a lifetime.

I have been dealing with this Disease for 40 years plus and I am excited to see what is happening with this dementia and these products.

My husband passed away one year ago with this dementia and his Mother before him. We sure need all the help we can get for this one.

JC, thanks so very very much for your interest and help with this one and this forum will be a great help to us all.
« Last Edit: April 30, 2008, 09:16:08 PM by JC Spencer »

Offline JC Spencer

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TREHALOSE - Educational Paper by JC Spencer
« Reply #1 on: March 01, 2008, 11:51:41 AM »
The following is a paper that have written and posted on our EndowmentMed.org site. We will begin our referencing to trehalose with this.

TREHALOSE -  Educational Information Only.  No medical claims are intended or implied.

Trehalose is a naturally occurring sugar energy source with forty percent to forty-five percent (40% to 45%) the sweetness of sucrose.  It is a white crystalline powder (trehalose dehydrate) produced from cornstarch by a patented enzymatic Hayashibara process.  An independent panel of experts determined Trehalose to be generally recognized as safe (GRAS) for use in foods in accordance with current good manufacturing practices.  This was submitted to the FDA and they responded with a "no objection" letter.  Canada approved trehalose as a food in 2005; it is now approved in over 40 countries world wide.

Trehalose is consumed in very small amounts in a normal diet through eating mushrooms, honey, lobster, and foods produced using bakers and brewer's yeast.

A clinical study performed in the UK showed that ninety-eight percent (98%) of the population had no problems with trehalose.  The other two percent (2%) experienced only a little gas.

Studies show that trehalose strengthens the cell membrane in plants and animals where it is found naturally.  More studies are needed to determine the benefits of trehalose in humans.  The author hopes to substantiate his belief that human cell membrane is strengthened by the presence of trehalose.  That fact has been proven in the lab where human cell membranes were put under extreme stress.  Verification of the strengthening of human cell membrane with trehalose in living humans is needed.  The significants of this finding, in the author's deduction, is that benefits in cell to cell communication could be improved because it is on and through the cell membrane that the glycoprotein receptor sites reside.  Glycoprotein receptor sites on the cell surface have been likened to trees on the surface of the earth.  Perhaps it is not too far fetched to consider the trehalose nourishment to the cell membrane as improving the "top soil" for the glycoprotein receptors.

Trehalose has been tested to produce lower insulin and blood glucose responses than glucose.  This verifies that the disaccharide bond is not broken by the digestive system.  Research is ongoing to elucidate the relationship between metabolic parameters and the potential energy and performance benefits of trehalose.

Charles Eschweiler, Director of Research and Technical Writer for The Endowment for Medical Research, made an interesting discovery through his ongoing literature research:  sufferers of Huntington's Chorea, a polyglutamine storage disorder with a genetic basis, benefit from the disaccharide trehalose.  Among the science papers he reviewed were trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease and Sweet Relief for Huntington's disease.

The same mechanism of action involving trehalose that worked in the Huntington's Chorea genetic knockout mice study may also be at work with other similar conditions such as Alzheimer's and Parkinson disease. Mr. Eschweiler also became aware that current research is ongoing with the United States Department of Defense to perfect a means of stabilizing battlefield blood supplies with trehalose.  Trehalose is noted primarily for its association with desert life forms that can be fully dehydrated, yet be brought back to life even after an interval of as much as 2,500 years.

The trehalose structural formula is a non-reducing disaccharide of two glucose molecules bonded by a ?, ?-1, 1 glycosidic link.  Trehalose is stable at low pH conditions and is non-hygroscopic, which results in a free-flowing dry crystal that is stable to ninety-four percent (94%) humidity.  It has a clean profile, which means it has no aftertaste.

Note: The editor is sorry that this software does not allow for scientific symbols to be displayed here. Instead, a ? is inserted.  You pay request a pdf file of this article.

(c) Copyright  2005, 2006, 2007, 2008 by J. C. Spencer
« Last Edit: May 06, 2008, 08:26:43 PM by JC Spencer »